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KURU WAS SHOWN TO BE TRANSMISSIBLE BY A CHIMP TEST

Cycle diagram of how kuru passed from a sick woman through funeral feasts back to new cases

THIS NEWSLETTER IS FOR INFORMATIONAL PURPOSES ONLY. NOTHING IN THIS CONTENT CONSTITUTES MEDICAL, PSYCHOLOGICAL, OR PROFESSIONAL ADVICE. ALWAYS CONSULT A QUALIFIED HEALTHCARE PROFESSIONAL BEFORE MAKING ANY HEALTH RELATED DECISIONS.

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OKAY BACK FROM THE FIELD CAMP 🏕️

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SORCERY WAS THE FORE EXPLANATION 🔮

Kuru Was A Fatal Shaking Disease Among The Fore Of Papua New Guinea

The Fore Believed Sorcerers Were Responsible For The Calamity

In 1961 And 1962 They Spent Much Time Trying To Find Them

That Search Cost Material Wealth And Emotional Energy

The Fore Took Sick People On Healing Trips To Distant Curers

Their Most Striking Trips Went To The Neighbouring Gimi People

More Than 70 Patients Consulted A Gimi Curer In 1961

Those Visits Came Between April And August

The Treatment Included Bloodletting And Medicinal Barks And Leaves

That Curer Also Named Where The Guilty Sorcerer Might Be Found

Back Home Sick Women Sometimes Named Their Attacker After A Dream

With Women Present Men Ran Divination Tests To Reveal The Sorcerers

Some Tests Suggested The Sorcerers Might Be Close Neighbours

That Often Led To New Tensions

The Fore Began Holding Public Meetings To Denounce Sorcery

At Those Meetings They Spoke About Past Animosities

The Main Debate Was Whether Kuru Was A Sickness Or Sorcery

One Anthropologist Wrote As The Kuru Epidemic Drew To A Close

By Then Kuru Sorcerers Were No Longer Believed In

A Few Fore Even Spoke Of Kuru As A Form Of Sickness

Yet Their Views About Sorcery In General Did Not Change

Researcher John Mathews Gave A Different Account

He Wrote That Most Fore Still Blame Sorcery For Kuru

The Fore Saw The Evidence That Led Science To Blame Eating The Dead

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DOCTORS FAVORED A GENETIC CAUSE 🐑

By 1961 Medical Investigators Most Favored A Genetic Explanation

Henry Bennett Was One Of The First To Propose It

A Grant He Provided Let Two Anthropologists Start Work In July 1961

The Two Were Robert Glasse And Shirley Lindenbaum

Bennett Expected Fore Family Records To Confirm His Theory

Instead Many Victims Turned Out Not To Be Closely Related By Blood

They Were Kin In A Sense That Was Not Biological

The Anthropologists' 1962 Data Suggested Kuru Reached Villages Slowly

That Had Happened Within Living Memory

Its Progress Through Fore Territory Followed A Traceable Route

Mathews Later Observed That Kuru Was Too Common

It Was Also Too Fatal To Be A Purely Genetic Disorder

That Would Need A Mechanism Keeping A Kuru Gene At High Frequency

No Evidence Existed For Such A Mechanism

Years Earlier A Clue Had Come From An American Scientist In England

William Hadlow Studied Scrapie For The US Department Of Agriculture

Scrapie Is A Slow Brain Disease Of Sheep And Goats

In June 1959 A Friend Told Him About A Museum Exhibit In London

Five Days Later Hadlow Saw The Exhibit Himself

The Exhibit At The Wellcome Medical Museum Was On Kuru

Hadlow Then Wrote A Letter That Ran In The Lancet In September 1959

It Pointed Out A Striking Similarity Between Kuru And Scrapie

He Suggested Kuru Might Be Transmissible After A Long Incubation

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THE CHIMPANZEE INOCULATION TEST 🐒

Mathews Named Two Reasons Carleton Gajdusek Turned To Primates

One Was Hadlow's Observation About Kuru And Scrapie

The Other Was The Anthropologists' Suggestion Of A Slow Infection

Gajdusek Led A Research Group At The National Institutes Of Health

Brain Material From A Kuru Patient Was Injected Into A Chimpanzee

It Went Directly Into The Animal's Brain

The First Chimpanzee To Fall Ill Was Named Georgette

Georgette Developed Symptoms Of Kuru In May 1965

That Was Just 20 Months After The Inoculation

The Experimental Transmission Was Reported In 1966

Hadlow Wrote That This Made The Link With Scrapie More Certain

Kuru Became The First Human Prion Disease Shown To Be Transmissible

Before 1966 The Anthropologists' Findings Drew Little Attention

That Attention Was Often Sceptical

The Anthropologists' Idea Was That Kuru Was Caught By Eating The Dead

In 1966 The Chimp Test Gave That Idea Credence

One Review Says The Chimpanzee Work Won Gajdusek A Nobel Prize

A Colleague Tied The Prize Instead To A Related Disease Called CJD

He Shared The 1976 Prize With Baruch Blumberg

It Was For New Mechanisms Of How Infectious Diseases Arise And Spread

The End

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